The regiment was called to active federal service on 17 February 1941, 10 months prior to the attack on Pearl Harbor.

After years of training, the unit first entered the continent of Europe on the Normandy beaches following the D-Day landing.

It became the 112th Infantry Regimental Combat Team which consisted of the 112th Infantry Regiment, the 229th Field Artillery Battalion, the 103rd Engineer Battalion, Company C, 447th Antiaircraft Artillery Battalion, and Company C, 630th Tank Destroyer Battalion.

28th Division commander James E. Wharton was in his first day of command when a German sniper shot him while he was at the 112th Infantry's command post.

The regiment plowed through France and Germany, participating in the capture of Paris and the bitter fighting in the Huertgen Forest. During December 1944, the 112th Infantry Regimental Combat Team was holding a 6-1/2 mile long sector which the Germans attacked with nine Divisions.

The Combat Team inflicted 1600 casualties and destroyed eighteen tanks during nine days of continuous action, that was later known as the Battle of the Bulge.

The regiment was awarded battle streamers marked Normandy, Northern France, Ardennes-Alsace, Rhineland, and Central Europe for its service in World War II. The unit was also awarded the Distinguished Unit Citation for its actions during the Battle of the Bulge, from 16 to 24 December 1944.

The unit was mustered out of federal service on 6 December 1945 at Camp Gordon, Georgia. 

A great invasion force stood off the Normandy coast of France as dawn broke on 6 June 1944: 9 battleships, 23 cruisers, 104 destroyers, and 71 large landing craft of various descriptions as well as troop transports, mine sweepers, and merchantmen—in all, nearly 5,000 ships of every type, the largest armada ever assembled.

The naval bombardment that began at 0550 that morning detonated large minefields along the shoreline and destroyed a number of the enemy’s defensive positions. To one correspondent, reporting from the deck of the cruiser HMS Hillary, it sounded like “the rhythmic beating of a gigantic drum” all along the coast.

In the hours following the bombardment, more than 100,000 fighting men swept ashore to begin one of the epic assaults of history, a “mighty endeavor,” as President Franklin D. Roosevelt described it to the American people, “to preserve. . . our civilization and to set free a suffering humanity.”

As July 1944 entered its final week, Allied forces in Normandy faced, at least on the surface, a most discouraging situation. In the east, near Caen, the British and Canadians were making little progress against fierce German resistance.

In the west, American troops were bogged down in the Norman hedgerows. These massive, square walls of earth, five feet high and topped by hedges, had been used by local farmers over the centuries to divide their fields and protect their crops and cattle from strong ocean winds.

The Germans had turned these embankments into fortresses, canalizing the American advance into narrow channels, which were easily covered by antitank weapons and machine guns.

The stubborn defenders were also aided by some of the worst weather seen in Normandy since the turn of the century, as incessant downpours turned country lanes into rivers of mud.

By 25 July, the size of the Allied beachhead had not even come close to the dimensions that pre–D-day planners had anticipated, and the slow progress revived fears in the Allied camp of a return to the static warfare of World War I.

Few would have believed that, in the space of a month and a half, Allied armies would stand triumphant at the German border.

The Rhineland Campaign, although costly for the Allies, had clearly been ruinous for the Germans. The Germans suffered some 300,000 casualties and lost vast amounts of irreplaceable equipment.

Hitler, having demanded the defense of all of the German homeland, enabled the Allies to destroy the Wehrmacht in the West between the Siegfried Line and the Rhine River. Now, the Third Reich lay virtually prostrate before Eisenhower’s massed armies.

In August 1944, while his armies were being destroyed in Normandy, Hitler secretly put in motion actions to build a large reserve force, forbidding its use to bolster Germany’s beleaguered defenses. To provide the needed manpower, he trimmed existing military forces and conscripted youths, the unfit, and old men previously untouched for military service during World War II.

In September Hitler named the port of Antwerp, Belgium, as the objective. Selecting the Eifel region as a staging area, Hitler intended to mass twenty-five divisions for an attack through the thinly held Ardennes Forest area of southern Belgium and Luxembourg.

Once the Meuse River was reached and crossed, these forces would swing northwest some 60 miles to envelop the port of Antwerp. The maneuver was designed to sever the already stretched Allied supply lines in the north and to encircle and destroy a third of the Allies’ ground forces. If successful, Hitler believed that the offensive could smash the Allied coalition, or at least greatly cripple its ground combat capabilities, leaving him free to focus on the Russians at his back door.

By the beginning of the Central Europe Campaign of World War II, Allied victory in Europe was inevitable. Having gambled his future ability to defend Germany on the Ardennes offensive and lost, Hitler had no real strength left to stop the powerful Allied armies. Yet Hitler forced the Allies to fight, often bitterly, for final victory.

Even when the hopelessness of the German situation became obvious to his most loyal subordinates, Hitler refused to admit defeat. Only when Soviet artillery was falling around his Berlin headquarters bunker did the German Fuehrer begin to perceive the final outcome of his megalomaniacal crusade.